Local Suppression of T Cell Responses by Arginase-Induced L-Arginine Depletion in Nonhealing Leishmaniasis

The balance between T helper (Th) 1 and Th2 cell responses is a major determinant of the outcome of experimental leishmaniasis, but polarized Th1 or Th2 responses are not sufficient to account for healing or nonhealing. Here we show that high arginase activity, a hallmark of nonhealing disease, is p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Modolell, Manuel, Choi, Beak-San, Ryan, Robert O., Hancock, Maggie, Titus, Richard G., Abebe, Tamrat, Hailu, Asrat, Müller, Ingrid, Rogers, Matthew E., Bangham, Charles R. M., Munder, Markus, Kropf, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703824/
https://ncbi.nlm.nih.gov/pubmed/19597544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000480
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados