Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I

Transcription termination by RNA polymerase I in Saccharomyces cerevisiae is mediated by a ‘torpedo' mechanism: co-transcriptional RNA cleavage by Rnt1 at the ribosomal DNA 3′-region generates a 5′-end that is recognized by the 5′–3′ exonuclease Rat1; this degrades the downstream transcript and...

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Detalhes bibliográficos
Main Authors: Braglia, Priscilla, Heindl, Katrin, Schleiffer, Alexander, Martinez, Javier, Proudfoot, Nick J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948184/
https://ncbi.nlm.nih.gov/pubmed/20814424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.130
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