Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia

BACKGROUND: Deregulation of microRNA may contribute to hematopoietic malignancies. MicroRNA-196b (miR-196b) is highly expressed in MLL-rearranged leukemia and has been shown to be activated by MLL and MLL-fusion genes. DESIGN AND METHODS: In order to determine whether high expression of miR-196b is...

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Main Authors: Schotte, Diana, Lange-Turenhout, Ellen A.M., Stumpel, Dominique J.P.M., Stam, Ronald W., Buijs-Gladdines, Jessica G.C.A.M., Meijerink, Jules P.P., Pieters, Rob, Den Boer, Monique L.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948092/
https://ncbi.nlm.nih.gov/pubmed/20494936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.023481
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