Malignant Transformation of Non-Neoplastic Barrett's Epithelial Cells through Well-Defined Genetic Manipulations

BACKGROUND: Human Barrett's cancer cell lines have numerous, poorly-characterized genetic abnormalities and, consequently, those lines have limited utility as models for studying the early molecular events in carcinogenesis. Cell lines with well-defined genetic lesions that recapitulate various...

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Detalhes bibliográficos
Main Authors: Zhang, Xi, Yu, Chunhua, Wilson, Kathleen, Zhang, Hui Ying, Melton, Shelby D., Huo, Xiaofang, Wang, David H., Genta, Robert M., Spechler, Stuart J., Souza, Rhonda F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948040/
https://ncbi.nlm.nih.gov/pubmed/20927195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013093
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