HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

Iron is essential for a wide range of cellular processes. Here we show that the bZIP-type regulator HapX is indispensable for the transcriptional remodeling required for adaption to iron starvation in the opportunistic fungal pathogen Aspergillus fumigatus. HapX represses iron-dependent and mitochon...

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Detalhes bibliográficos
Main Authors: Schrettl, Markus, Beckmann, Nicola, Varga, John, Heinekamp, Thorsten, Jacobsen, Ilse D., Jöchl, Christoph, Moussa, Tarek A., Wang, Shaohua, Gsaller, Fabio, Blatzer, Michael, Werner, Ernst R., Niermann, William C., Brakhage, Axel A., Haas, Hubertus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947994/
https://ncbi.nlm.nih.gov/pubmed/20941352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001124
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