The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess

Balance of physiological levels of iron is essential for every organism. In Aspergillus fumigatus and other fungal pathogens, the transcription factor HapX mediates adaptation to iron limitation and consequently virulence by repressing iron consumption and activating iron uptake. Here, we demonstrat...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Gsaller, Fabio, Hortschansky, Peter, Beattie, Sarah R, Klammer, Veronika, Tuppatsch, Katja, Lechner, Beatrix E, Rietzschel, Nicole, Werner, Ernst R, Vogan, Aaron A, Chung, Dawoon, Mühlenhoff, Ulrich, Kato, Masashi, Cramer, Robert A, Brakhage, Axel A, Haas, Hubertus
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232046/
https://ncbi.nlm.nih.gov/pubmed/25092765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489468
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