Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons

Excessive inhibition of brain neurons in primary or slice cultures can induce homeostatic intrinsic plasticity, but the functional role and underlying molecular mechanisms of such plasticity are poorly understood. Here, we developed an ex vivo locus coeruleus (LC) slice culture system and successful...

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Bibliografiske detaljer
Main Authors: Cao, Jun-Li, Vialou, Vincent F., Lobo, Mary Kay, Robison, Alfred J., Neve, Rachael L., Cooper, Donald C., Nestler, Eric J., Han, Ming-Hu
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947876/
https://ncbi.nlm.nih.gov/pubmed/20837544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010077107
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