Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons

Excessive inhibition of brain neurons in primary or slice cultures can induce homeostatic intrinsic plasticity, but the functional role and underlying molecular mechanisms of such plasticity are poorly understood. Here, we developed an ex vivo locus coeruleus (LC) slice culture system and successful...

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Detalhes bibliográficos
Main Authors: Cao, Jun-Li, Vialou, Vincent F., Lobo, Mary Kay, Robison, Alfred J., Neve, Rachael L., Cooper, Donald C., Nestler, Eric J., Han, Ming-Hu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947876/
https://ncbi.nlm.nih.gov/pubmed/20837544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010077107
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