Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons

Excessive inhibition of brain neurons in primary or slice cultures can induce homeostatic intrinsic plasticity, but the functional role and underlying molecular mechanisms of such plasticity are poorly understood. Here, we developed an ex vivo locus coeruleus (LC) slice culture system and successful...

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Détails bibliographiques
Auteurs principaux: Cao, Jun-Li, Vialou, Vincent F., Lobo, Mary Kay, Robison, Alfred J., Neve, Rachael L., Cooper, Donald C., Nestler, Eric J., Han, Ming-Hu
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947876/
https://ncbi.nlm.nih.gov/pubmed/20837544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010077107
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