Variants in ACADIO are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians

AIMS/HYPOTHESIS: A prior genome-wide association study in Pima Indians identified a variant within the ACAD10 gene that is associated with early-onset type 2 diabetes. Acyl-coenzyme A dehydrogenase 10 (ACAD10) catalyses mitochondrial fatty acid beta-oxidation, which plays a pivotal role in developin...

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Hauptverfasser: Bian, L., Hanson, R. L., Muller, Y. L., Ma, L., Kobes, S., Knowler, W. C., Bogardus, C., Baier, L. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947857/
https://ncbi.nlm.nih.gov/pubmed/20390405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1695-y
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