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Development of a new Lewis base-tolerant chiral LBA and its application to catalytic asymmetric protonation reaction

A new Lewis base-tolerant LBA (Lewis Acid Assisted Brønsted Acid) derived from La(OTf)(3) and (S)-HOP has been developed as a new chiral Brønsted acid. This acid has been successfully applied as a catalyst to asymmetric protonation reactions of silyl enol ethers of 2-substituted cyclic ketones.

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Autori principali: Cheon, Cheol Hong, Imahori, Tatsushi, Yamamoto, Hisashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947798/
https://ncbi.nlm.nih.gov/pubmed/20730236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02492a
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