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Construction of Vicinal Tertiary and All Carbon Quaternary Centers by Catalytic Asymmetric Claisen Rearrangement of Enolphosphonates

A Cu-catalyzed enantioselective Claisen rearrangement of easily-accessible enolphosphonates using commercially available (R, R)-PhBOX as the chiral ligand was developed. A wide range of rearrangement products with contiguous tertiary and all carbon quaternary centers were obtained in excellent yield...

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Autores principales: Tan, Jiajing, Cheon, Cheol-Hong, Yamamoto, Hisashi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517105/
https://ncbi.nlm.nih.gov/pubmed/22821885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201203092
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