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Palladium-Catalyzed Asymmetric Construction of Vicinal All-Carbon Quaternary Stereocenters and its Application to the Synthesis of Cyclotryptamine Alkaloids

[Image: see text] We report the use of a two-fold Pd-catalyzed decarboxylative allylic alkylation (Pd-DAAA) to construct two vicinal all carbon quaternary stereocenters in a diastereo- and enantioselective fashion. To demonstrate the synthetic utility of this process, the products of the Pd-DAAA wer...

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Hlavní autoři: Trost, Barry M., Osipov, Maksim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825681/
https://ncbi.nlm.nih.gov/pubmed/23824625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201302805
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