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Planar cell polarity: the orientation of larval denticles in Drosophila appears to depend on gradients of Dachsous and Fat

The larval ventral belts of Drosophila consist of six to seven rows of denticles that are oriented, some pointing forwards, some backwards. We present evidence that denticle orientation is determined almost entirely by Dachsous and Fat, one of two planar cell polarity systems. If we change the distr...

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Autors principals: Repiso, Ada, Saavedra, Pedro, Casal, José, Lawrence, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947754/
https://ncbi.nlm.nih.gov/pubmed/20826534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.047126
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