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Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat

The Drosophila genes fat (ft) and dachsous (ds) encode large atypical cadherins that collaborate to coordinately polarize cells in the plane of the epithelium (planar cell polarity) and to affect growth via the Warts/Hippo pathway [1–3]. Ft and Ds form heterodimeric bridges that convey polarity info...

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Détails bibliographiques
Auteurs principaux: Brittle, Amy L., Repiso, Ada, Casal, José, Lawrence, Peter A., Strutt, David
Format: Artigo
Langue:Inglês
Publié: Cell Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958304/
https://ncbi.nlm.nih.gov/pubmed/20434337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.03.056
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