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Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat

The Drosophila genes fat (ft) and dachsous (ds) encode large atypical cadherins that collaborate to coordinately polarize cells in the plane of the epithelium (planar cell polarity) and to affect growth via the Warts/Hippo pathway [1–3]. Ft and Ds form heterodimeric bridges that convey polarity info...

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Autori principali: Brittle, Amy L., Repiso, Ada, Casal, José, Lawrence, Peter A., Strutt, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958304/
https://ncbi.nlm.nih.gov/pubmed/20434337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.03.056
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