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Liver-Specific β-Catenin Knockout Mice Have Bile Canalicular Abnormalities, Bile Secretory Defect and Intrahepatic Cholestasis

β-Catenin plays important roles in liver physiology and hepatocarcinogenesis. While studying the role of β-catenin in diet-induced steatohepatitis, we recently found that liver-specific β-catenin knockout (KO) mice exhibit intrahepatic cholestasis. This study was undertaken to further characterize t...

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Bibliografiske detaljer
Main Authors: Yeh, Tzu-Hsuan, Krauland, Lindsay, Singh, Vijay, Zou, Baobo, Devaraj, Prathab, Stolz, Donna B., Franks, Jonathan, Monga, Satdarshan P. S., Sasatomi, Eizaburo, Behari, Jaideep
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947599/
https://ncbi.nlm.nih.gov/pubmed/20722001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23801
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