Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis

Although the role of Wnt/β-catenin signaling in liver growth and development is well established, its contribution in non-neoplastic hepatic pathologies has not been investigated. Here, we examine the role of β-catenin in a murine model of diet-induced liver injury. Mice with hepatocyte-specific β-c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Behari, Jaideep, Yeh, Tzu-Hsuan, Krauland, Lindsay, Otruba, Wade, Cieply, Benjamin, Hauth, Beth, Apte, Udayan, Wu, Tong, Evans, Rhobert, Monga, Satdarshan P.S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808081/
https://ncbi.nlm.nih.gov/pubmed/20019186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090667
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker