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R-ETODOLAC DECREASES BETA-CATENIN LEVELS ALONG WITH SURVIVAL AND PROLIFERATION OF HEPATOMA CELLS

BACKGROUND: Inhibition of hepatoma cells by cyclooxygenase (COX)-2 dependent and independent mechanisms has been shown previously. Here, we examine the effect of Celecoxib, a COX-2-inhibitor and R-Etodolac, an enantiomer of the nonsteroidal anti-inflammatory drug Etodolac, which lacks COX-inhibitory...

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Detalhes bibliográficos
Main Authors: Behari, Jaideep, Zeng, Gang, Otruba, Wade, Thompson, Michael, Muller, Peggy, Micsenyi, Amanda, Sekhon, Sandeep S., Leoni, Lorenzo, Monga, Satdarshan P. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924913/
https://ncbi.nlm.nih.gov/pubmed/17275129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2006.11.017
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