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Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin

Basaloid skin tumors, including basal cell carcinoma (BCC) and basaloid follicular hamartoma (BFH), are associated with aberrant Hedgehog (Hh) signaling1 and, in the case of BCC, an expanding set of genetic variants including keratin 5 (K5)2, an intermediate filament-forming protein. We show that ge...

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Autors principals: DePianto, Daryle, Kerns, Michelle, Dlugosz, Andrzej A., Coulombe, Pierre A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947596/
https://ncbi.nlm.nih.gov/pubmed/20871598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.665
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