ERBB4 PROMOTES CYCLOOXYGENASE-2 EXPRESSION AND CELL SURVIVAL IN COLON EPITHELIAL CELLS

The ErbB4 receptor tyrosine kinase is expressed at high levels in human and mouse colitis, and inhibits colon epithelial cell apoptosis in the presence of pro-inflammatory cytokines. In this study, we investigated the molecular mechanisms responsible for ErbB4-induced cell survival. In cultured mous...

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Detalhes bibliográficos
Main Authors: Frey, Mark Ronald, Hilliard, Valda Catherine, Mullane, Matthew Travis, Polk, D. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947587/
https://ncbi.nlm.nih.gov/pubmed/20585313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.117
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