ERBB4 PROMOTES CYCLOOXYGENASE-2 EXPRESSION AND CELL SURVIVAL IN COLON EPITHELIAL CELLS

The ErbB4 receptor tyrosine kinase is expressed at high levels in human and mouse colitis, and inhibits colon epithelial cell apoptosis in the presence of pro-inflammatory cytokines. In this study, we investigated the molecular mechanisms responsible for ErbB4-induced cell survival. In cultured mous...

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Hlavní autoři: Frey, Mark Ronald, Hilliard, Valda Catherine, Mullane, Matthew Travis, Polk, D. Brent
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947587/
https://ncbi.nlm.nih.gov/pubmed/20585313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.117
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