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The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo
The unfolded protein response is a critical system by which the cell handles excess misfolded protein in the secretory pathway. The role of the system in modulating the effects of aggregation prone cytosolic proteins has received less attention. We use genetic reporters to demonstrate activation of...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947516/ https://ncbi.nlm.nih.gov/pubmed/20927324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013084 |
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