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The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo

The unfolded protein response is a critical system by which the cell handles excess misfolded protein in the secretory pathway. The role of the system in modulating the effects of aggregation prone cytosolic proteins has received less attention. We use genetic reporters to demonstrate activation of...

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Autors principals: Loewen, Carin A., Feany, Mel B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947516/
https://ncbi.nlm.nih.gov/pubmed/20927324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013084
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