Sprouty Proteins Inhibit Receptor-mediated Activation of Phosphatidylinositol-specific Phospholipase C

Sprouty (Spry) proteins are negative regulators of receptor tyrosine kinase signaling; however, their exact mechanism of action remains incompletely understood. We identified phosphatidylinositol-specific phospholipase C (PLC)-γ as a partner of the Spry1 and Spry2 proteins. Spry–PLCγ interaction was...

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Xehetasun bibliografikoak
Egile Nagusiak: Akbulut, Simge, Reddi, Alagarsamy L., Aggarwal, Priya, Ambardekar, Charuta, Canciani, Barbara, Kim, Marianne K.H., Hix, Laura, Vilimas, Tomas, Mason, Jacqueline, Basson, M. Albert, Lovatt, Matthew, Powell, Jonathan, Collins, Samuel, Quatela, Steven, Phillips, Mark, Licht, Jonathan D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2010
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947483/
https://ncbi.nlm.nih.gov/pubmed/20719962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-02-0123
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