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V-ATPase-Mediated Granular Acidification Is Regulated by the V-ATPase Accessory Subunit Ac45 in POMC-Producing Cells

The vacuolar (H(+))-ATPase (V-ATPase) is an important proton pump, and multiple critical cell-biological processes depend on the proton gradient provided by the pump. Yet, the mechanism underlying the control of the V-ATPase is still elusive but has been hypothesized to involve an accessory subunit...

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Detalhes bibliográficos
Main Authors: Jansen, Eric J. R., Hafmans, Theo G. M., Martens, Gerard J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947469/
https://ncbi.nlm.nih.gov/pubmed/20702583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-04-0274
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