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Versatile Roles of V-ATPases Accessory Subunit Ac45 in Osteoclast Formation and Function

Vacuolar-type H(+)-ATPases (V-ATPases) are macromolecular proton pumps that acidify intracellular cargos and deliver protons across the plasma membrane of a variety of specialized cells, including bone-resorbing osteoclasts. Extracellular acidification is crucial for osteoclastic bone resorption, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qin, An, Cheng, Tak S., Lin, Zhen, Pavlos, Nathan J., Jiang, Qing, Xu, Jiake, Dai, Ke R., Zheng, Ming H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210823/
https://ncbi.nlm.nih.gov/pubmed/22087256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027155
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