Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin αvβ5 Clustering and Turnover

Cell-to-extracellular matrix adhesion is regulated by a multitude of pathways initiated distally to the core cell–matrix adhesion machinery, such as via growth factor signaling. In contrast to these extrinsically sourced pathways, we now identify a regulatory pathway that is intrinsic to the core ad...

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Main Authors: Li, Zhilun, Lock, John G., Olofsson, Helene, Kowalewski, Jacob M., Teller, Steffen, Liu, Yajuan, Zhang, Hongquan, Strömblad, Staffan
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947468/
https://ncbi.nlm.nih.gov/pubmed/20719960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-03-0245
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