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Listeria monocytogenes that lyse in the macrophage cytosol trigger AIM2-mediated pyroptosis

To gain insight into the mechanisms by which host cells detect cytosolic invasion by intracellular pathogens, a genetic screen was performed to identify Listeria monocytogenes mutants that induced altered levels of host cell death. A mutation in lmo2473 resulted in hyper-stimulation of host cell dea...

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Bibliografski detalji
Glavni autori: Sauer, John-Demian, Witte, Chelsea E., Zemansky, Jason, Hanson, Bill, Lauer, Peter, Portnoy, Daniel A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947455/
https://ncbi.nlm.nih.gov/pubmed/20417169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.04.004
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