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Listeria monocytogenes that lyse in the macrophage cytosol trigger AIM2-mediated pyroptosis
To gain insight into the mechanisms by which host cells detect cytosolic invasion by intracellular pathogens, a genetic screen was performed to identify Listeria monocytogenes mutants that induced altered levels of host cell death. A mutation in lmo2473 resulted in hyper-stimulation of host cell dea...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947455/ https://ncbi.nlm.nih.gov/pubmed/20417169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.04.004 |
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