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Listeria monocytogenes that lyse in the macrophage cytosol trigger AIM2-mediated pyroptosis
To gain insight into the mechanisms by which host cells detect cytosolic invasion by intracellular pathogens, a genetic screen was performed to identify Listeria monocytogenes mutants that induced altered levels of host cell death. A mutation in lmo2473 resulted in hyper-stimulation of host cell dea...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947455/ https://ncbi.nlm.nih.gov/pubmed/20417169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.04.004 |
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