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Microtopographical Cues in 3D Attenuate Fibrotic Phenotype and Extracellular Matrix Deposition: Implications for Tissue Regeneration

Recent studies have highlighted the role of external biophysical cues on cell morphology and function. In particular, substrate geometry and rigidity in two dimensions has been shown to impact cell growth, death, differentiation, and motility. Knowledge of how these physical cues affect cell functio...

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Bibliographic Details
Main Authors: Ayala, Perla, Lopez, Jose I., Desai, Tejal A.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947433/
https://ncbi.nlm.nih.gov/pubmed/20235832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2009.0815
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