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Microtopographical Cues in 3D Attenuate Fibrotic Phenotype and Extracellular Matrix Deposition: Implications for Tissue Regeneration

Recent studies have highlighted the role of external biophysical cues on cell morphology and function. In particular, substrate geometry and rigidity in two dimensions has been shown to impact cell growth, death, differentiation, and motility. Knowledge of how these physical cues affect cell functio...

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Detalhes bibliográficos
Main Authors: Ayala, Perla, Lopez, Jose I., Desai, Tejal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947433/
https://ncbi.nlm.nih.gov/pubmed/20235832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2009.0815
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