Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by RGS proteins 4 or 8 and 7 in permeabilised C6 cells is Gα subtype dependent

Regulators of G protein signaling (RGS) proteins act as GTPase accelerating proteins (GAPs) to negatively modulate G protein signaling and are defined by a conserved RGS domain with considerable amino acid diversity. To determine the effects of specific, purified RGS proteins on mu-opioid signaling,...

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Main Authors: Talbot, Jeffery N., Roman, David L., Clark, Mary J., Roof, Rebecca A., Tesmer, John J.G., Neubig, Richard R., Traynor, John R.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947325/
https://ncbi.nlm.nih.gov/pubmed/20002516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06519.x
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