Differential Effect of Membrane Cholesterol Removal on μ- and δ-Opioid Receptors: A PARALLEL COMPARISON OF ACUTE AND CHRONIC SIGNALING TO ADENYLYL CYCLASE

According to the lipid raft theory, the plasma membrane contains small domains enriched in cholesterol and sphingolipid, which may serve as platforms to organize membrane proteins. Using methyl-β-cyclodextrin (MβCD) to deplete membrane cholesterol, many G protein-coupled receptors have been shown to...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Levitt, Erica S., Clark, Mary J., Jenkins, Paul M., Martens, Jeffrey R., Traynor, John R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
Mechanisms of Signal Transduction
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755935/
https://ncbi.nlm.nih.gov/pubmed/19520863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030411
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