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Differential Effect of Membrane Cholesterol Removal on μ- and δ-Opioid Receptors: A PARALLEL COMPARISON OF ACUTE AND CHRONIC SIGNALING TO ADENYLYL CYCLASE

According to the lipid raft theory, the plasma membrane contains small domains enriched in cholesterol and sphingolipid, which may serve as platforms to organize membrane proteins. Using methyl-β-cyclodextrin (MβCD) to deplete membrane cholesterol, many G protein-coupled receptors have been shown to...

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Detalhes bibliográficos
Main Authors: Levitt, Erica S., Clark, Mary J., Jenkins, Paul M., Martens, Jeffrey R., Traynor, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755935/
https://ncbi.nlm.nih.gov/pubmed/19520863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030411
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