Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

We have generated mouse models of non-Hodgkin lymphoma (NHL) that rely on the cooperation between MYC overexpression and B-cell antigen receptor (BCR) signaling for the initiation and maintenance of B-cell lymphomas. Using these mouse models of NHL, we have focused on the identification of BCR-deriv...

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Main Authors: Young, Ryan M., Hardy, Ian R., Clarke, Raedun L., Lundy, Nicolai, Pine, Polly, Turner, Brian C., Potter, Terry A., Refaeli, Yosef
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Lymphoid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947310/
https://ncbi.nlm.nih.gov/pubmed/18981293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158618
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