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Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate

Retinal degeneration causes vision impairment and blindness in humans. If one day we are to harness the potential of stem cell–based cell replacement therapies to treat these conditions, it is imperative that we better understand normal retina development. Currently, the genes and mechanisms that re...

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Autors principals: Liu, Wei, Lagutin, Oleg, Swindell, Eric, Jamrich, Milan, Oliver, Guillermo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947236/
https://ncbi.nlm.nih.gov/pubmed/20890044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43219
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