Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development

In vertebrate embryos, formation of anterior neural structures requires suppression of Wnt signals emanating from the paraxial mesoderm and midbrain territory. In Six3(−/−) mice, the prosencephalon was severely truncated, and the expression of Wnt1 was rostrally expanded, a finding that indicates th...

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Bibliographic Details
Main Authors: Lagutin, Oleg V., Zhu, Changqi C., Kobayashi, Daisuke, Topczewski, Jacek, Shimamura, Kenji, Puelles, Luis, Russell, Helen R.C., McKinnon, Peter J., Solnica-Krezel, Lilianna, Oliver, Guillermo
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC195989/
https://ncbi.nlm.nih.gov/pubmed/12569128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1059403
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