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A phospholipid-apolipoproteinA-I nanoparticle containing Amphotericin B as a drug delivery platform with cell membrane protective properties

Amphotericin B (AMB), a potent antifungal agent, has been employed as an inhalable therapy for pulmonary fungal infections. We recently described a novel nano-sized delivery vehicle composed of phospholipid (PL) and apolipoprotein A-I, NanoDisk (ND), to which we added AMB as a payload (ND-AMB). The...

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Autors principals: Burgess, Braydon L., Cavigiolio, Giorgio, Fannucchi, Michelle V., Illek, Beate, Forte, Trudy M., Oda, Michael N.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946961/
https://ncbi.nlm.nih.gov/pubmed/20696226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.07.057
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