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Anti-EGFRvIII monoclonal antibody armed with (177)Lu: in vivo comparison of macrocyclic and acyclic ligands

INTRODUCTION: Monoclonal antibody (mAb) L8A4 binds specifically to the epidermal growth factor receptor variant III (EGFRvIII) that is present on gliomas but not normal tissues, and is internalized rapidly after receptor binding. Because of the short range of its β-emissions, labeling this mAb with(...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hens, Marc, Vaidyanathan, Ganesan, Zhao, Xiao-Guang, Bigner, Darell D., Zalutsky, Michael R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946893/
https://ncbi.nlm.nih.gov/pubmed/20870149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.04.020
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