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Anti-EGFRvIII monoclonal antibody armed with (177)Lu: in vivo comparison of macrocyclic and acyclic ligands
INTRODUCTION: Monoclonal antibody (mAb) L8A4 binds specifically to the epidermal growth factor receptor variant III (EGFRvIII) that is present on gliomas but not normal tissues, and is internalized rapidly after receptor binding. Because of the short range of its β-emissions, labeling this mAb with(...
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Egile Nagusiak: | , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
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2010
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946893/ https://ncbi.nlm.nih.gov/pubmed/20870149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.04.020 |
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