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Interaction of FKBP5 with Childhood Adversity on Risk for Post-Traumatic Stress Disorder
FKBP5 regulates the cortisol-binding affinity and nuclear translocation of the glucocorticoid receptor. Polymorphisms at the FKBP5 locus have been associated with increased recurrence risk of depressive episodes and rapid response to antidepressant treatment. A recent study showed that FKBP5 genotyp...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946626/ https://ncbi.nlm.nih.gov/pubmed/20393453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.37 |
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