Interaction of FKBP5 with Childhood Adversity on Risk for Post-Traumatic Stress Disorder

FKBP5 regulates the cortisol-binding affinity and nuclear translocation of the glucocorticoid receptor. Polymorphisms at the FKBP5 locus have been associated with increased recurrence risk of depressive episodes and rapid response to antidepressant treatment. A recent study showed that FKBP5 genotyp...

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Bibliographic Details
Main Authors: Xie, Pingxing, Kranzler, Henry R, Poling, James, Stein, Murray B, Anton, Raymond F, Farrer, Lindsay A, Gelernter, Joel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946626/
https://ncbi.nlm.nih.gov/pubmed/20393453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.37
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