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Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP(+) Toxicity in Neuronal Cells

Mitochondrial dysfunction is involved in the pathogenesis of neurodegenerative diseases, including Parkinson’s disease (PD). Uncoupling proteins (UCPs) delink ATP production from biofuel oxidation in mitochondria to reduce oxidative stress. UCP2 is expressed in brain, and has neuroprotective effects...

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Detalhes bibliográficos
Main Authors: Ho, Philip Wing-Lok, Liu, Hui-Fang, Ho, Jessica Wing-Man, Zhang, Wei-Yi, Chu, Andrew Chi-Yuen, Kwok, Ken Hon-Hung, Ge, Xuan, Chan, Koon-Ho, Ramsden, David Boyer, Ho, Shu-Leong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946553/
https://ncbi.nlm.nih.gov/pubmed/19763737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-009-9109-y
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