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Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP(+) Toxicity in Neuronal Cells
Mitochondrial dysfunction is involved in the pathogenesis of neurodegenerative diseases, including Parkinson’s disease (PD). Uncoupling proteins (UCPs) delink ATP production from biofuel oxidation in mitochondria to reduce oxidative stress. UCP2 is expressed in brain, and has neuroprotective effects...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946553/ https://ncbi.nlm.nih.gov/pubmed/19763737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-009-9109-y |
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