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Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2.
In mammalian brown adipose tissue, thermogenesis is explained by uncoupling mitochondrial respiration from ATP synthesis. Uncoupling protein-1 (UCP1) is responsible for this uncoupled state, because it allows proton re-entry into the matrix and thus dissipates the proton gradient generated by the re...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171648/ https://ncbi.nlm.nih.gov/pubmed/10545094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.5827 |
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