Uncoupling Protein-4 (UCP4) Increases ATP Supply by Interacting with Mitochondrial Complex II in Neuroblastoma Cells

Mitochondrial uncoupling protein-4 (UCP4) protects against Complex I deficiency as induced by 1-methyl-4-phenylpyridinium (MPP(+)), but how UCP4 affects mitochondrial function is unclear. Here we investigated how UCP4 affects mitochondrial bioenergetics in SH-SY5Y cells. Cells stably overexpressing...

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Detalhes bibliográficos
Main Authors: Ho, Philip Wing-Lok, Ho, Jessica Wing-Man, Tse, Ho-Man, So, Danny Hon-Fai, Yiu, David Chi-Wai, Liu, Hui-Fang, Chan, Koon-Ho, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303587/
https://ncbi.nlm.nih.gov/pubmed/22427795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032810
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