Accelerated production of antigen-specific T-cells for pre-clinical and clinical applications using Gas-permeable Rapid Expansion cultureware (G-Rex)

The clinical manufacture of antigen-specific cytotoxic T lymphocytes (CTL) for adoptive immunotherapy is limited by the complexity and time required to produce large numbers with the desired function and specificity. The culture conditions required are rigorous, and in some cases only achieved in 2c...

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Main Authors: Vera, Juan F., Brenner, Lara J., Gerdemann, Ulrike, Ngo, Minhtran C., Sili, Uluhan, Liu, Hao, Wilson, John, Dotti, Gianpietro, Heslop, Helen E., Leen, Ann M., Rooney, Cliona M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946348/
https://ncbi.nlm.nih.gov/pubmed/20445351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181c0c3cb
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