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Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity

BACKGROUND: An ideal tumor vaccine should activate both effector and memory immune response against tumor-specific antigens. Beside the CD8+ T cells that play a central role in the generation of a protective immune response and of long-term memory, dendritic cells (DCs) are important for the inducti...

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Detalhes bibliográficos
Main Authors: Cerkovnik, Petra, Novakovic, Barbara Jezersek, Stegel, Vida, Novakovic, Srdjan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946268/
https://ncbi.nlm.nih.gov/pubmed/20836870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-11-45
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