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Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype
BACKGROUND: Cystic fibrosis (CF) is caused by mutations in the CFTR gene that impair the function of CFTR, a cAMP-regulated anion channel. In the small intestine loss of CFTR function creates a dehydrated, acidic luminal environment which is believed to cause an accumulation of mucus, a phenotype ch...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945989/ https://ncbi.nlm.nih.gov/pubmed/20843337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-107 |
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