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Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype

BACKGROUND: Cystic fibrosis (CF) is caused by mutations in the CFTR gene that impair the function of CFTR, a cAMP-regulated anion channel. In the small intestine loss of CFTR function creates a dehydrated, acidic luminal environment which is believed to cause an accumulation of mucus, a phenotype ch...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: De Lisle, Robert C, Mueller, Racquel, Roach, Eileen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945989/
https://ncbi.nlm.nih.gov/pubmed/20843337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-107
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