Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans.

Nitric oxide (NO) is an inhibitor of gastrointestinal smooth muscle. Model systems of the gut predict the NO will complex with biological thiol (SH) groups, yielding S-nitrosothiols (RS-NO), which may limit the propensity to form mutagenic nitrosamines. The inhibitory effects of NO and its biologica...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Slivka, A, Chuttani, R, Carr-Locke, D L, Kobzik, L, Bredt, D S, Loscalzo, J, Stamler, J S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294570/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7525649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117527
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