Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans.

Nitric oxide (NO) is an inhibitor of gastrointestinal smooth muscle. Model systems of the gut predict the NO will complex with biological thiol (SH) groups, yielding S-nitrosothiols (RS-NO), which may limit the propensity to form mutagenic nitrosamines. The inhibitory effects of NO and its biologica...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Slivka, A, Chuttani, R, Carr-Locke, D L, Kobzik, L, Bredt, D S, Loscalzo, J, Stamler, J S
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7525649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117527
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