Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans.

Nitric oxide (NO) is an inhibitor of gastrointestinal smooth muscle. Model systems of the gut predict the NO will complex with biological thiol (SH) groups, yielding S-nitrosothiols (RS-NO), which may limit the propensity to form mutagenic nitrosamines. The inhibitory effects of NO and its biologica...

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發表在:	J Clin Invest
Principais autores:	Slivka, A, Chuttani, R, Carr-Locke, D L, Kobzik, L, Bredt, D S, Loscalzo, J, Stamler, J S
格式:	Artigo
語言:	Inglês
出版:	American Society for Clinical Investigation 1994
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7525649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117527
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